Effect of Streptozotocin (STZ) on Pancreatic Carcinogenisis
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چکیده
منابع مشابه
Effects of Sesamin on Streptozotocin (STZ)-Induced NIT-1 Pancreatic β-Cell Damage
The protective effect of sesamin (SES) from sesame meal on NIT-1 pancreatic β-cells damaged by streptozotocin (STZ) in vitro was investigated. The cell viability, insulin secretion, the activity of superoxide dismutase(SOD), glutathione peroxidase (GSHpx) and the content of reduced glutathione (GSH) increased significantly when incubated with SES (400, 200 µg mL-1). The content of malondialdehy...
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this experimental study has been conducted to test the effect of oral presentation on the development of l2 learners grammar. but this oral presentation is not merely a deductive instruction of grammatical points, in this presentation two hypotheses of krashen (input and low filter hypotheses), stevicks viewpoints on grammar explanation and correction and widdowsons opinion on limited use of l1...
15 صفحه اولStreptozotocin (STZ) mediates acute upregulation of serum and pancreatic osteopontin (OPN): a novel islet-protective effect of OPN through inhibition of STZ-induced nitric oxide production.
Osteopontin (OPN) is a secreted acidic phosphoprotein that binds to a cell-surface integrin-binding motif and is involved in many inflammatory and immune-modulating disorders. There is compelling evidence that soluble OPN can in a variety of situations help cells survive an otherwise lethal insult. In this study we show that OPN is localized in the rat pancreatic islets and ducts. Staining of p...
متن کاملThe effect of leaf extract P.harmala on streptozotocin-induced apoptosis in pancreatic tissue of rats
Abstract Background and Purpose: Decreased beta-cell mass has a role in the pathogenesis of human type 2 diabetes and in rodent diabetes models. The study of plant extracts is important as they possibly inhibit the reduction of beta cell mass and the islets of Langerhans. The effect of the methanolic extract of P. harmala leaves on pancreatic tissue was investigated in this research. Method: A ...
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ژورنال
عنوان ژورنال: Cancer therapy & Oncology International Journal
سال: 2017
ISSN: 2473-554X
DOI: 10.19080/ctoij.2017.07.555725